Mirtazapine vs Zopiclone | Which Is Stronger?

Medically Reviewed

We’ve all felt blue from time to time because sadness is a part of life. You may have failed a test, lost a pet, or, even worse, had a close relative pass away. At some point in a healthy brain, however, we begin to cope with and overcome these emotions. Depression is prevalent during puberty because our hormones are out of control. Like normal feelings of sadness, we eventually grow out of these and move on. For others, it’s not that simple.

According to the Mayo Clinic, major depressive disorders, or clinical depression, are mood disorders that cause persistent feelings of sadness and a loss of interest in life. As the condition worsens, it will begin to affect how you think, feel, and behave. It usually leads to various emotional and physical issues, and you might begin to notice problems conducting normal day-to-day activities. In some cases, you may even feel that life is not worth living.

Depression is not a “feeling” that will go away. Instead, it is a chemical imbalance in the brain that can only be treated by medication. One such medicine is known as mirtazapine, which falls under a group of drugs called tetracyclic antidepressants. Researchers don’t fully understand how the drug works, but it is thought to affect communications between the nerve cells and restore chemical balance in the brain. Sometimes, these are accompanied by sleep medications like zopiclone to help with the sleep aspect.

Depression has also been linked to insomnia, which is common. Nearly 15 percent of adults have chronic insomnia, and almost the same number of individuals struggle with depression.

Depression and insomnia go hand in hand, and even though 15 percent of those with depression sleep too much, a staggering 80 percent will have trouble falling asleep or staying asleep. Individuals with insomnia are almost three times more likely to develop a depressive disorder.

The relationship between the two disorders is complicated, but insomnia is considered a symptom of depression. The initial thought was to treat the underlying depression, and sleep problems would vanish. Unfortunately, that’s not always the case.

Is Mirtazapine or Zopiclone Stronger?

You may be prescribed both medications, or maybe you’ve spoken with your doctor about options to treat your depression and insomnia.

Your doctor might have mentioned zopiclone and mirtazapine, which may have left you wondering which of the drugs is stronger.

The National Institutes of Health has released a study describing that mirtazapine could be an effective treatment of insomnia. Since chronic insomnia is a risk factor for suicidal ideation, the therapeutic benefit of targeting insomnia is crucial.

It’s challenging to determine which drug is stronger because they are two completely different drugs. On the one hand, zopiclone can only treat insomnia, while in studies, mirtazapine has been shown to treat both disorders.

Based on this alone, you could feel comfortable saying that mirtazapine is the stronger medicine because it addresses two disorders, while its counterpart can only treat one.

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